Anti Estrogen Steroids Powder Exemestane Aromasin 99% Purity CAS
Exemestane is known as a hormonal breast cancer
treatment.Exemestane decreases the amount of estrogen the body
makes and helps to slow or reverse the growth of these breast
cancers.This medication is used to treat certain types of breast
cancer (such as hormone-receptor-positive breast cancer) in women
after menopause. Exemestane is also used to help prevent the cancer
from returning. Some breast cancers are made to grow faster by a
natural hormone called estrogen.
1. Quick Details:
|Appearance:||White to almost white powder|
Exemestane is known as a hormonal breast cancer treatment.
Some breast cancers need the hormone oestrogen to grow. In women
who have been through the menopause, the main source of oestrogen
is through the change of sex hormones called androgens into
oestrogen. An enzyme called 'aromatase' is needed for this change
to occur. Exemestane works by inhibiting (or blocking) this enzyme.
This reduces the amount of oestrogen in your body, which slows the
growth of the cancer cells.
3. Fuction of Exemestane:
1) Exemestane for breast cancer prevention:
Chemoprevention of breast cancer is an effective strategy to reduce
the incidence of this disease in women at risk. The first agents to
show a significant chemopreventive effect were the SERMs tamoxifen
and raloxifen. An updated comprehensive analysis of all SERM
prevention trials showed that they are able to reduce the incidence
of breast cancer in high- and average-risk women, an effect that is
sustained by a reduction in ER-positive invasive breast cancer.
2) Exemestane is a third-generation irreversible steroidal
inactivator of the aromatase enzyme and is effective in all the
treatment settings for breast cancer, including chemoprevention.
In the metastatic setting, exemestane has been extensively
investigated as the first-line, second-line, and further-line
treatment and is now registered for the treatment of postmenopausal
women with advanced hormone-receptor-positive breast cancer whose
disease has progressed following antiestrogen therapy. Of note, the
potential lack of cross-resistance with NSAIs yields additional
opportunities in the treatment sequence of endocrine agents.
Furthermore, based on clinically meaningful results, exemestane
with everolimus represents an effective therapeutic option for a
disease that has progressed after exposure to NSAIs.
Exemestane is generally well tolerated, with a side effect profile
similar to that of other AIs and including menopausal symptoms,
arthralgia, bone loss, and altered lipid metabolism.
4. How to Take Exemestane:
Before you start this treatment, read the manufacturer's printed
information leaflet from inside your pack. The manufacturer's
leaflet will give you more information about exemestane and a full
list of the side-effects which you may experience from taking it.
Take one 25 mg tablet of exemestane each day, exactly as your
doctor tells you to. Your dose will be printed on the label of the
tablet pack to remind you.
Swallow the tablet with a drink of water, straight after a meal.
You may take exemestane with whichever meal of the day you find
easiest to remember, but try to take your doses with the same meal
each day. This will help you to avoid missing any doses.
If you forget to take a dose at your usual time, take it as soon as
you remember. If you do not remember until the following day, skip
the missed dose. Do not take two doses together to make up for a
Continue to take the tablets regularly each day until your doctor
tells you otherwise. You may need to take exemestane for a number
This is dependent on the individual and, also, the amount of
aromatizing compounds the person is running. Generally, a good
starting dose is 12.5mg ED (every day) or 25mg EOD (every other
day). The user must utilize blood work to see how their body is
reacting at the starting dosage they choose and then adjust as
needed. Experienced anabolic steroid users will usually find a dose
they like and stick to it with no problems. As I said already, if
you start noticing joint issues then the dose should be lowered; on
the other hand, if you start noticing any estrogen related sides,
such as puffy or sensitive breasts or water retention, it's time to
increase the dosage.
According to literature, the half life is 25-27 hours, which means
you can easily get away with taking this drug every other day or
once a day.
|Description||White Crystalline Powder||White Powder|
|Loss On Drying||0.5%max||0.19%|
|Specific Rotation||+288°~ +298°||+290.2°|
|Residue On Ignition||0.1%max||0.03%|
|Heavy Metals||20PPm max||<10PPm|
|Conclusion||The specification conform with USP35|
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|Product name||CAS number|
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